“Canada at the Forefront” edition, Stream Neurosciences feature
BIOTECanada Insights magazine — Spring 2026
Discovery of Novel Benzothiazole-Based PDE4 Inhibitors for Central Nervous System Disorders.
Meng L, Liang SH — 6 April 2026 (issue 14 May 2026)
Northern Illinois University and Stream Neuroscience report PDE4 inhibitors
BioWorld Science — 8 October 2025
Zebrafish: Breakthroughs In Epilepsy Drug Discovery?!
Neuroscientist Prof. Deborah Kurrasch from the University of Calgary talks about her research into the epilepsies using zebrafish!
Inhibition of phosphodiesterase 4B as a novel therapeutic strategy for the treatment of refractory epilepsy.
Kinch CD, Kesler M, Dogra DD, Morin K, Ibhazehiebo K, Noschang CG, Rho JM, Kurrasch DM — 17 May 2025 (preprint)
Bringing ‘One Brain’ research to market for better brain health
University of Calgary news release — 19 April 2018
Selective allosteric inhibition of phosphodiesterase 4B (PDE4B) as a potential anti-seizure treatment for Dravet Syndrome
Kinch, CD, et al., American Epilepsy Society 2024 Dec
A concise synthesis of biaryl PDE4D allosteric modulators
Dalby, A, et al.,Tetrahedron Lett. 2013
LINK IS NO LONGER AVAILABLE
kcna1a Mutant Zebrafish model episodic Ataxia type 1 (EA1) with epilepsy and show response to first-line therapy carbamazepine
Dogra, D., Epilepsia 2018 Mar
UCalgary researchers use new approach in precision medicine to screen anti-seizure drugs for children”
Education News Canada, University of Calgary